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Pathology Hypersensitivity f46abde9

Which of the following potentially represents the most dangerous situation?

A
Rh+ve mother with 2nd Rh-ve child
B
Rh-ve mother with 2nd Rh+ve child
C
Rh+ve mother with 1st Rh-ve child
D
Rh-ve mother with 1st Rh+ve child
High-Yield Explanation
* Rh-ve mother with 2nd Rh+ve child can result in the development of hemolytic disease of newborn or erythroblastosis fetalis. So, it is a dangerous condition. * This condition is a type II hypersensitivity reaction. * This is Not to be confused with Hemorrhagic disease of the newborn which is a coagulation disturbance in the newborns due to vitamin K deficiency. As a consequence of vitamin K deficiency there is an impaired production of coagulation factors II, VII, IX, X, C and S by the liver.

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