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Unknown General f448c169

Bioavailability of Ramelteon is?

A
2%
B
7%
C
10%
D
30%
High-Yield Explanation
Reference: Goodman & Gilman's The Pharmacological Basis of Therapeutics, 12th ed., Pg. 1972. Ramelteon is rapidly absorbed orally, undergoes extensive first pass metabolism in liver, so that bioavailability is low (F = 1.8%) and elimination t½ is 1–3 hours.

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