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Pharmacology Cardiovascular system f43e66a1

The following statement is not true about sotolol

A
It is non selective Beta blocker
B
It prolongs the action potential duration throughout the hea
C
It is excreted through bile following hepatic metabolism
D
Polymorphic ventricular tachycardia is a common problem
High-Yield Explanation
Refer kDT 6/e 140,515 sotolol is a non selective Beta blocker (potassium channel blocker) class 3 antiarrhythmic propey. It prolongs APD by blocking the cardiac potassium channels. Therefore prolongs QT interval and results in torsedes points ( polymorphic ventricular tachycardia) It is lipid insoluble Beta blocker that is excreted predominantly by kidney.

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