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Biochemistry General f43a992b

Which of the following is not the source of cytosolic NADPH ?

A
Isocitrate dehydrogenase
B
ATP citrate lyase
C
Malic enzyme
D
G6PD
High-Yield Explanation
Answer. B. ATP citrate lyaseNADPH is a cofactor used in anabolic reactions, such as lipid and nucleic acid synthesis, which require NADPH as a reducing agent.The major source of NADPH in animals and other non-photosynthetic organisms is the pentose phosphate pathway.The key enzymes in these processes are: NADP-linked malic enzyme, NADP-linked isocitrate dehydrogenase, NADP-linked glutamate dehydrogenase and nicotinamide nucleotide transhydrogenase.

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