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Pathology General f40da3ff

Hypercoagulation in nephrotic syndrome is caused by?

A
Loss of antithrombin III
B
Decreased fibrinogen
C
Decreased metabolism of Vitamin K
D
Increase in protein C
High-Yield Explanation
Ans. is 'a' i.e., Loss of antithrombin III Causes of Hypercoagulability in nephrotic syndrome o Loss of antithrombin III o Increased synthesis of fibrinogen by liver. o Altered activity of protein C and S o Increased platelet aggregability. o Hypercoagulability can cause renal vein thrombosis.

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