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Pathology General f40455e5

A 28 year old female patient who is a lactating mother and has a history of hepatectomy reported for follow up. Which of the following cellular adaptations will be seen in this patient?

A
Hypertrophy of liver + Hypertrophy of breast
B
Hypertrophy and hyperplasia of liver + Hypertrophy of breast
C
Hyperplasia of liver + Hyperplasia of breast
D
Hyperplasia of liver + Hyperplasia and hypertrophy of breast
High-Yield Explanation
Hypertrophy:- → Increase in size and functions of cells. → Results due to increase in growth factor or trophic stimuli. → Includes puberty, lactating breasts and skeletal muscle fibers (in bodybuilders). Hyperplasia:- → Increase in number of cells (in tissue) organ. → Results due to increase in growth factors, increased expression of growth-promoting genes and increased DNA synthesis. → It persists as long as stimulus is present. Eg:- Breast development at puberty, endometrial hyperplasia, benign hyperplasia of prostate, hypertrophy of liver cells after partial hepatectomy.

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