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Biochemistry General f3e23903

Which of the following is true for phosphofructokinase?

A
It uses Fructose 1,6 bisphosphate as substrate.
B
It generates ATP
C
It catalyses an irreversible reaction in glycolysis
D
It is activated by increased levels of ATP and citrate.
High-Yield Explanation
Phosphofructokinase catalyses the first committed step of glycolysis. It is the rate limiting enzyme of glycolysis. The reaction is irreversible.

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