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Microbiology All India exam f3d843c2

"Anhedonia" seen in schizophrenia is linked to which of the following neurotransmitter abnormality?

A
Serotonin
B
Dopamine
C
Glutamate
D
GABA
High-Yield Explanation
Anhedonia refers to the reduced ability to experience pleasure.In animal models severe stress causes nucleus accumbens dopamine neurons to become insensitive to CRF (Coicotropin-Releasing Factor), resulting in reduced dopamine release and increased anhedonia.(Ref: Kaplan and Sadock&;s synopsis of psychiatry Pg 290)

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