What is most common cause of death in amyloidosis?
High-Yield Explanation
Hea. Amyloidosis of the hea may occur either as isolated organ involvement or as pa of a systemic distribution. When accompanied by systemic involvement, it is usually of the AL form. The isolated form (senile amyloidosis) usually is confined to older persons. The deposits may not be evident on gross examination, or they may cause minimal to moderate cardiac enlargement. The most characteristic gross findings are gray-pink, dewdrop-like subendocardial elevations, paicularly evident in the atrial chambers. On histologic examination, deposits typically are found throughout the myocardium, beginning between myocardial fibers and eventually causing their pressure atrophy Robbins 9 th edition page no. 157