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Biochemistry Metabolism of lipid f386a4f6

The enzyme ^9 desaturase catalyzes the conversion of stearic acid into?

A
Linolenic acid
B
Linoleic acid
C
Oleic acid
D
All of the above
High-Yield Explanation
The enzyme ^9 desaturase, in endoplasmic reticulum, catalyzes conversion of stearic acid to oleic acid, which is a MUFA. ^9 desaturase is a mixed-function oxidase, requiring NADPH and O2. Humans cannot introduce double bonds beyond ^9 position (between C10 and terminal methyl group). Hence, linoleic (D9,12 ) and linolenic acid (D 9,12,15) are considered essential fatty acids. Reference: Harper's Illustrated Biochemistry 30th Edition Pg 239

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