HOX gene mutation can cause all except

Hox genes (a subset of homeotic genes) are a group of related genes that control the body plan of an embryo along the cranio-caudal (head-tail) axis. After the embryonic segments have formed, the Hox proteins determine the type of segment structures (e.g. legs, antennae, and wings in fruit flies or the different types of veebrae in humans) that will form on a given segment. Hox proteins thus confer segmental identity, but do not form the actual segments themselves.A ventricular septal defect (VSD) is a defect in the ventricular septum, the wall dividing the left and right ventricles of the hea. The extent of the opening may vary from pin size to complete absence of the ventricular septum, creating one common ventricle. The ventricular septum consists of an inferior muscular and superior membranous poion and is extensively innervated with conducting cardiomyocytes. The membranous poion, which is close to the atrioventricular node, is most commonly affected in adults and older children in the United States.] It is also the type that will most commonly require surgical intervention, comprising over 80% of cases. Membranous ventricular septal defects are more common than muscular ventricular septal defects, and are the most common congenital cardiac anomaly