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Biochemistry General f3649eea

The MOST common enzyme deficiency responsible for Galactosemia is related to which of the following enzymes?

A
UDP galactose epimerase
B
Galactokinase
C
Galactosidase
D
Galactose-l-phosphate uridyl transferase
High-Yield Explanation
Galactose-1-phosphate uridyltransferase (GALT) deficiency is the most common enzyme deficiency that causes hypergalactosemia. Hereditary galactosemia is among the most common carbohydrate metabolism disorders and can be a life-threatening illness during the newborn period. Ref: Liver Disease in Children By Frederick J. Suchy, Ronald J. Sokol, William F. Balistreri, 2007, Page 596; Textbook of Biochemistry and Human Biology by L. M. Srivastava, Page 353; Saunders manual of pediatric practice by Laurence Finberg, Ronald E. Kleinman, Page 238

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