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Pharmacology Anti-Parasitic Drugs f3538c89

Which of the following statements about miltefosine is True?

A
It is used only for visceral leishmaniasis
B
A 4 week course produces cure rate of around 65%
C
It is the oral drug for treatment of kala-azar
D
It is safe in pregnancy
High-Yield Explanation
MILTEFOSINE - It is the first oral drug for treatment of kala azar. - 4 weeks course can produce cure rates of more than 95 percent - It can be used for visceral as well as cutaneous leishmaniasis. - It has a very long half life. - Reversible derangements of LFT and KFT have been noted. - Miltefosine is teratogenic and is contraindicated in pregnancy. Female is advised to avoid pregnancy till 3 months after miltefosine course.

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