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Pediatrics Viral Infections f3412336

According to WHO the major sign of AIDS in chil- dren in stage I is the following -

A
Generalised lymphadenopathy
B
Not gaining weight
C
Oral candidiasis
D
All of above
High-Yield Explanation
Ans. is 'a' i.e.. Generalised lymph adenopathy Revised WHO clinical staging of HI V,'A IDS for infants and childreno Clinical Stage 1AsymptomaticPersistent generalized Lymphadenopathyo Clinical Stage 2HepatosplenomegalyPapular pruritic eruptionsSeborrhoeic dermatitisExtensive human papilloma virus infectionExtensive molluscum contagiosumFungal nail infectionsRecurrent oral ulcerationsLineal gingival erythema (LGE)Angular cheilitisParotid enlargementHerpes zosterRecurrent or chronic RTIs (otitis media, otorrhoea, sinusitis)o Clinical Stage 3Moderate unexplained malnutrition not adequately responding to standard therapyUnexplained persistent diarrhoea (14 days or more )Unexplained persistent fever (intermittent or constant, for longer than one month)Oral candidiasis (outside neonatal period )Oral hairy leukoplakiaAcute necrotizing ulcerative gingivitis-periodontitisPulmonary TBSevere recurrent presumed bacterial pneumonia Conditions where con?rmatory diagnostic testing is necessaryChronic HIV-associated lung disease including bronchiectasisLymphoid interstitial pneumonitis (LIP)Unexplained anaemia (<8g/dl), and or neutropenia (<1000/mm3) and or thrombocytopenia (<50 000/ mm3) for more than one montho Clinical Stage 4Unexplained severe wasting or severe malnutrition not adequately responding to standard therapyPneumocystis pneumoniaRecurrent severe presumed bacterial infections (e.g. empyema, pvomyositis, bone or joint infection, meningitis, but excluding pneumonia).Chronic herpes simplex infection; (orolabial or cutaneous of more than one month's duration)Extrapulmonaiy TBKaposi's sarcomaOesophageal candidiasisCNS toxoplasmosis (outside the neonatal period)HIV encephalopathyConditions where confirmatory diagnostic testing is necessaryCMV infection (CMV retinitis or infection of organs other than liver, spleen or lymph nodes; onset at age one month or more)Extrapulmonaiy cryptococcosis including meningitisAny disseminated endemic mycosis (e.g. extrapulmonaiy' histoplasmosis, coccidiomycosis, penicilliosis)CryptosporidiosisIsosporiasisDisseminated non-tuberculous mycobacteria infectionCandida of trachea, bronch i or lungsVisceral herpes simplex infectionAcquired HIV associated rectal fistulaCerebral or B cell non-Hodgkin lymphomaProgressive multifocal leukoencephalopathy (PML)HIV-associated cardiomyopathy or HIV-associated nephropathy

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