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Pediatrics Inborn Errors of Metabolism f3140eee

A child with low blood glucose is not able to do glycogenolysis or gluconeogenesis. Which of the following enzyme is missing in the child?

A
Fructokinase
B
Glucokinase
C
Glucose 6-phosphatase
D
Transketolase
High-Yield Explanation
c. Glucose 6 phosphatase(Ref: Nelson's 20/e p 715, Ghai 8/e p 655)Glycogenolysis or gluconeogenesis is mediated by glucose 6 phosphatase which is absent in Von Gierke disease.

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