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Biochemistry Miscellaneous (Bio-Chemistry) f2cd26a8

Tryptophan deficiency leads to:

A
Her's disease
B
Lesch Nyhan syndrome
C
Hartnup disease
D
Alkaptonuria
High-Yield Explanation
(C) Hartnup disease # Hartnup disease occurs due to impaired intestinal absorption and renal re-absorption of a neutral amino acid, tryptophan.> Tryptophan is required for synthesis of serotonin and nicotinic acid.> Neurological manifestations of Hartnup disease are due to decreased synthesis of serotonin while pellagra-like rash occurs due to decreased synthesis of nicotinic acid.> Her's disease (choice A) is caused by deficiency of liver phosphorylase.

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