Drug of choice in acute mania is:

DOC of acute mania- antipsychotic However if in exam, you have an option of mood stabilizer plus antipsychotic, that would become the preferred answer. E.g. If in this question , there was an option of lithium plus risperidone, that would have been the best answer In absence of combination, we would chose antipsychotics. Atypical antipsychotics like risperidone are preferred over typical antipsychotics like chlorpromazine, because of better side effect profile