A patient with human immunodeficiency virus (HIV) infection has progressed to developing AIDS (clinical category C). Which of the following conditions is considered an AIDS-defining illness?
High-Yield Explanation
The current case definition of AIDS in a patient with HIV infection is done by symptoms and CD4+ T-lymphocyte cell count. Any category C symptoms (e.g., cervical cancer, mycobacterium avium infection, CMV, retinitis, Kaposi sarcoma, etc.) indicates frank AIDS as does a CD4+ T-cell count <200/mL regardless of symptoms. Shingles and thrush are category B symptoms.