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Pathology Haematology f24167a3

Warm antibody hemolytic anemia is seen in all expect-

A
Methyl dopa
B
Penicillin
C
Quinidine
D
Stibophen
High-Yield Explanation
Warm antibody type hemolytic anaemia can be induced by drugs. A small poion of patients receiving methyl dopa develop AIHA .They are tolerance breaking drugs Penicillin antibiotics develop antibodies agaist RBC , drug complex which induces hemolysis. Quinidine forms a complex with plasma protein to which an antibody forms This complex may induce lysis of bystanding RBC or platelets. Stibophen is an antihelminthic drug which cannot induce AIHA. REFERENCE; HARSH MOHAN TEXTBOOK OF PATHOLOGY, 7TH EDITION.PG NO. 289.

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