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Medicine General f20978ee

True about Post-Streptococcal Glomerulonephritis is:

A
50% of cases occur after pharyngitis
B
Early treatment of Pharyngitis eliminates the risk of P.S.G.N.
C
Glomerulonephritis, secondary to skin infection, is more common in summer
D
Recurrence is seen
High-Yield Explanation
Answer is C (Glomerulonephritis secondary to skin infection is more common in Summer): 'During cold weather post streptococcal glomerulonephritis commonly follows streptococcal pharyngitis; whereas during warm weather, the G.N. generally follows streptococcal skin infection or pyoderma'. "Early systemicantibiotic therapy of Streptococcal throat and skin infection will NOT eliminate the risk of glomerulonephritis". Nelson 15th / 1488 "Recurrence are extremely rare" Nelson 15th / 1488 ......Immunity to strains causing G.N. is type-specific and long-lasting, and hence repeated infection and nephritis are rare. Post streptococcal glomerulonephritis may follow either pharyngitis or, skin infection (pyoderma) with a nephritogenic strain of group A beta haemolytic streptococci. I could not however, find what percentage of PSGN cases follow pharyngitis and what percentage follow skin infections. . All I could gather was that these incidences are relative, depending upon the climatic conditions of the area concerned such that in the tropics, skin infection is more impoant than pharyngitis as a cause. The epidemic forms, on the other hand, are seen in children of 2-6 years of age, and are secondary to pharyngitis. Thus no exact demarcation in terms of percentages can be made.

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