38-year-old man Babbu, a chronic alcoholic, presents with pain in the abdomen. On examination, his liver is enlarged and serum alpha-fetoprotein is elevated. The most likely diagnosis is -

Increase in α feta protein is associated with hepatocellular carcinoma and chronic alcoholism is a well known and common predisposing factor. Clinical Feature In most cases, hepatocellular carcinoma presents as an ill defined upper abdominal pain, malaise, fatigue and weakness and sometimes awareness of an abdominal mass or abdominal fullness. On palpation, the enlarged liver may be felt as a Unifocal usually large mass Multifocal widely distributed nodules of variable size. Diffuse infiltrative cancer.