In sickle cell anemia all are true except-
High-Yield Explanation
In sickle cell anemia , the peripheral blood demonstrates numbers of irreversibly sickled cells , reticulocytes and target cells , which results from red cell dehydration.Howell Jolly bodies (small Nuclear remanants)are also present. Ref : Robbins pathologic basis of disease 9th edition: pg636 ;under heading morphology