Full 2L QBank
Biochemistry General f088a859

Which of the following apoproteins activate esterification of cholesterol?

A
Apo E
B
Apo C
C
Apo A1
D
Apo B100
High-Yield Explanation
Apo A1, the major apoprotein in HDL activates LCAT(Lecithin cholesterol acyltransferase).The discoid HDL whoich has mainly ApoA1 receives cholesterol from the peripheral tissues which is estrified by LCAT.Esterification makes the cholesterol hydrophobic and is pushed to the core of HDL.As more and more cholesterol is taken up and esterified,the HDL becomes spherical. Ref: Bersot T.P. (2011). Chapter 31. Drug Therapy for Hypercholesterolemia and Dyslipidemia. In B.C. Knollmann (Ed), Goodman & Gilman's The Pharmacological Basis of Therapeutics, 12e.

Related Biochemistry MCQs

Practice 2,00,000+ NEET PG Questions Free

Timed mock tests, mistake queue analytics, audio lectures & zero attempt limits on i❤️Exams.

Start Free Mock Test Now