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Microbiology Systemic Bacteriology (Gram Positive Bacilli, Gram Negative Bacilli) f04bc5db

The diphtheria toxin has an affinity for all the following tissues EXCEPT

A
Myocardium
B
Brain
C
Adrenals
D
Liver
High-Yield Explanation
The diphtheria toxin is the sole virulence factor of C. diphtheriae. Responsible for both local effects and systemic complications. It is encoded by a lysogenic beta-prophage. It inhibits mammalian protein synthesis (ribosomal function) ADP ribosylation of EF-2 It has a special affinity for myocardium, adrenals and nerve endings

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