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General Medicine General f04549d1

A 20-year-old male presented to the OPD with recurrent episodes of lower backache which was more in morning and relieved on movement. Patient gave history of multiple episodes of chest infections in the past for which the patient was hospitalized multiple times. On ophthalmoscopic examination, iritis and conjunctivitis were noted. Lab findings revealed HLA-B27 positivity, elevated CRP and elevated ESR. The doctor ordered the x-ray of the lumbar spine and performed a test. Which of the following interleukins is most commonly involved in the pathogenesis of the above disease: -

A
IL-1
B
IL-17
C
IL-5
D
IL-10

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