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Biochemistry General f03fd3b5

Acetyl CoA carboxylase enzyme is present in ?

A
Cytosol
B
Mitochondria
C
Nucleus
D
Lysosome
High-Yield Explanation
Ans. is 'a' i.e., Cytosol This question is slightly different from previous one. The major acetyl CoA carboxylase which is involved in lipogenesis is acetyl CoA Carboxylase-1 (ACC-1). It is a cytosolic enzyme. In general acetyl CoA carboxylase refers to ACC-1. There is one more isoform of acetyl CoA carboxylase, i.e. ACC-2. Which is present in muscle, allowing muscle to regulate b-oxidation. ACC-2 is present in mitochondria.

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