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Physiology Endocrine System f013122e

Hypeonic dehydration would result from:

A
G.I. fluid loss
B
Diabetes mellitus
C
Primary hypoadrenocoicalism
D
SIADH
High-Yield Explanation
ECF disturbance are of 2 types: Dehydration Overhydration DEHYDRATION: Isotonic dehydration Water & Na+ lost in equal propoion no shift of H2O k/o isotonicity of ECF seen in: GI fluid loss Burns Hemorrhage Hypeonic dehydration: H2O lost from ECF ECF becomes hypeonic H2O moves from ICF to ECF, and intracellular volume decreases seen in: Alcoholism Diabetes mellitus, diabetes insipidus. Hypotonic dehydration: H2O & Na+ lost but Na loss >>> H2O loss ECF becomes hypotonic, H2O moves to ICF compament causing secondary increase in ICF volume seen in: 1deg hypoaldosteronism 1deg hypoadrenocoicism OVERHYDRATION / VOLUME EXPANSION: Isotonic overhydration: k/o administration of oral / IV isotonic saline Hypeonic overhydration: Administration of oral / IV hypeonic saline Hypotonic overhydration: SIADH - excess ADH secreted in euvolemic states that result in hypervolemia

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