Which of the following does not cause pulmonary hypeension?
High-Yield Explanation
Hyperventilation REF: Harrison 17th ed. chapter 244 Fenfluramine is known to cause PAH Pulmonary aerial hypeension (PAH) 1.1. Idiopathic (IPAH) (formerly PPH) 1.2. Familial (FPAH) 1.3. Associated with (APAH): 1.3.1. Collagen vascular disease 1.3.2. Congenital systemic-to- pulmonary shunts 1.3.3. Poal hypeension 1.3.4. HIV infection 1.3.5. Drugs and toxins 1.3.6. Other (thyroid disorders, glycogen storage disease, Gaucher disease, hereditary hemorrhagic telangiectasia, hemoglobinopathies, myeloproliferative disorders, splenectomy) 1.4. Associated with significant venous or capillary involvement 1.4.1. Pulmonary veno-occlusive disease (PVOD) 1.4.2. Pulmonary capillary hemangiomatosis (PCH) 1.5. Persistent pulmonary hypeension of the newborn 2. Pulmonary hypeension with left hea disease 2.1. Left-sided atrial or ventricular hea disease 2.2. Left-sided valvular hea disease 3. Pulmonary hypeension associated with lung diseases and/or hypoxemia 3.1. Chronic obstructive pulmonary disease 3.2. Interstitial lung disease 3.3. Sleep-disordered breathing 3.4. Alveolar hypoventilation disorders 3.5. Chronic exposure to high altitude 3.6. Developmental abnormalities 4. Pulmonary hypeension due to chronic thrombotic and/or embolic disease 4.1. Thromboembolic obstruction of proximal pulmonary aeries 4.2. Thromboembolic obstruction of distal pulmonary aeries 4.3. Nonthrombotic pulmonary embolism (tumor, parasites, foreign material) 5. Miscellaneous Sarcoidosis, histiocytosis X, lymphangiomatosis, compression of pulmonary vessels (adenopathy, tumor, fibrosing mediastinitis)