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Biochemistry General efd3774a

Which enzyme polymerises okazaki fragments ?

A
DNA polymerase I
B
DNA polymerase II
C
DNA polymerase III
D
RNA polymerase
High-Yield Explanation
Ans. is 'c' i.e., DNA polymerase III Two DNA polymerases act on Okazaki fragments :? DNA polymerase :- Causes polymerization of okazaki fragments, i.e. synthesis of DNA on lagging strand. It also causes synthesis of leading strand. DNA polymerase I :- It fills the gap between okazaki fragments when their polymerization is completed, i.e. when the synthesis on lagging strand is completed, DNA polymerase I fills the gap between fully polymerized okazaki fragments. Thus, DNA polymerase III is involved during 'elongation' (polymerization of okazaki fragments) and DNA polymerase I is involved during 'termination' (filling the gaps between okazaki fragments).

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