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Physiology Transport Across Cell Membrane ef7cf618

Which of them is TRUE about Na+-K+ pump:

A
K+ is pumped against the gradient.
B
2K+ are exchanged with 5Na+
C
Hypercalcemia causes arrest in Na+ K+ pump.
D
Increase in intracellular Na+ increases action potential.
High-Yield Explanation
Ans. is 'a' i.e. K+ is pumped against the gradient Na+-K+ pump or Na+-K+ ATPase, extrude 3 Na+ from the cell and take 2 K+ into the cell. *Thus its coupling ratio is 3:2.It pumps both Na+ & K+ against their concentration gradients by utilizing energy from the hydrolysis of ATRBecause of this differences in the charges moved in and out, it is an electrogenic pump. *Increase in intracellular Na+, decrease the height of action potential.

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