Gynaecology & Obstetrics Congenital malformations ef735315 SRY gene is located on: A Sho arm of Y chromosome B Long arm of Y chromosome C Sho arm of X chromosome D Long arm of X chromosome High-Yield Explanation Robbins basic pathology 6th edition. Chapter Genetic disorders. page no.174. sry gene- sex determining region Y gene is located on the distal sho arm of Y chromosome . so option 1 is right.