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Pharmacology General ef591abc

A patient has subclinical folate deficiency. Which of the following drug cannot precipitate megaloblastic anemia in this patient?

A
Alcohol
B
Metformin
C
Proguanil
D
Chloroquine
High-Yield Explanation
Megaloblastic anaemia can be caused by a deficiency of folic acid or vitamin B12. The drugs that can result in a deficiency of folic acid include: B – B12 and folic acid deficiency A – Alcohol T – Trimethoprim S – Sulfasalazine M – Metformin A – Antifolates (Methotrexate, pyrimethamine, proguanil) N – N2O

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