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Physiology Endocrinology ef24d120

Which of the following is not directly controlled by ACTH?

A
Glucocoicoids
B
Androstenedione
C
Dehydroepiandrosterone
D
Epinephrine
High-Yield Explanation
THe secretion of the adrenal medullary hormones(epinephrine, norepinephrine and dopamine) is not controlled directly by ACTH. ACTH controls mainly secretion of adrenal coical hormones: Glucoicoids (coisol, coicosterone) and sex steroids (testosterone, DHEA, androstenedione ). Note: The major regulators of aldosterone are angiotensim II and potassium. However, ACTH can also stimulate aldosterone prooduction. Hormones secreted Regulated by Zona glomerulosa Mineralocoicoids (aldosterone) Angiotesin II, K+ Zona fasiculata Glucocoticoids (coisol, coicosterone) ACTH Zona Reticularis Sex steroids (DHEA, DHEA-S) ACTH Adrenal medulla Catecholamines(Epinephrine, norepinephrine) DIffuse sympathetic discharge(stress) REf: Guyton and Hall 13th edition Pgno: 965,966

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