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Pharmacology General ef036642

Which of the following interacts with Digitalis maximally-

A
Furosemide
B
Triamterene
C
Amiloride
D
Spironolactone
High-Yield Explanation
Ans. is 'a' i.e., Furosemide o Two classes of diuretics are given in the options Loop Diuretics -----> Furosemide (cause hypokalemia) Potassium sparing diuretics ----> Spironolactone, Trimetrene, Amiloride (cause Hyperkalemia) We know that digitalis toxicity is potentiated by hypokalemia. So the drug interacting with digitalis will be Furosemide as it causes Hypokalemia.

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