A cancer patient who is on cisplatin therapy develops severe vomiting on the 1st day of treatment, drug indicated to treat this is:

Cisplatin induced vomiting has two phases. EarlyPhase: It occurs within first 24 hours. 5 HT3 antagonists like ondansetron are the agents of choice for this condition. Delayed Phase: Vomiting occurring after 24 hours is less responsive to ondansetron and other drugs. It is best controlled by substance P antagonist like aprepitant