Curschmann's crystals are seen in -

Pathology of Asthma Gross - Lungs are overdistended because of overinflation and there may be a small area of atelectasis. The most striking macroscopic finding is occlusion of bronchi and bronchioles by thick tenacious mucus plugs. Histology - Characterized by the presence of numerous eosinophils and neutrophils. Curschmann's spiral - Whorls of shed epithelium in mucous plugs. Charcot -Leyden crystals - Collection of crystalloids made up of eosinophilic membrane protein. The other characteristic histological finding of Asthma is collectively called Airway remodelling, it includes - Thickening of the basement membrane of the bronchial epithelium. Edema and an inflammatory infiltrate in the bronchial walls with a prominence of eosinophils and mast cells. An increase in the size of submucosal glands. Hypertrophy of bronchial wall muscle. The "airway remodelling" contributes to airflow obstruction.