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Pediatrics General eec3212c

Feature of hemorrhagic disease of new born is ?

A
Prolonged prothrombin time
B
Defective platelet count
C
Prolonged bleeding time
D
Prolonged thrombin time
High-Yield Explanation
Ans. is 'a' i.e., Prolonged prothrombine timeo Normal new borns are moderately deficient in vitamin K.o This deficiency increases on 3'd 51h day when, vitamin K level falls fuher. The serum level of vitamin K stas increasing from 13th to 15th day of life and achieves adult level at 3 months.o This is normal, and does not produce any bleeding.o In hemorrhagic disease of the newborn there is delay in achieving the normal vitamin K level. Clinical Featureso Vitamin K deficiency produces severe bleeding.o Bleeding occurs from umbilical cord stump on 2"d/3rd day after bih.o Intracranial bleding and large intramuscular hemorrhages may occur.o Increased prothrombin time and increased paial thromboplastin time.T/To Parenteral vitamin K therapy.

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