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Pharmacology Cytotoxic Anticancer Drugs ee803e31

Which anti-cancer drug affects DNA as well as RNA?

A
5-FU
B
Methotrexate
C
Actinomycin-D
D
Etoposide
High-Yield Explanation
Actinomycin-D is one of the anti-tumor antibiotic. It has two mechanisms of action: - It blocks RNA transcription by interfering with template function of DNA. - It causes single strand breaks in the DNA. It is used in the treatment of Wilm's tumor and rhabdomyosarcoma.

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