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Gynaecology & Obstetrics General ee481b50

Initiation of lactation is affected by :

A
Progesterone
B
Prolactin
C
HPL
D
All
High-Yield Explanation
Ans is a, b and c Prolactin; HPL; and Progesterone Lactation can be divided into 3 stages : Stage I : Mammogenesis - Mammary growth and development Hormones responsible : Growth Main hormone Suppoing hormones Ductal growth Oestrogen Growth hormone and glucocoicoids Alveolar growth Progesterone Prolactin, prednisolone and other (in the oestrogen primed breast) growth promoting factors Stage ii : Lactogenesis : Initiation of milk secretion Main hormone responsible : Prolactin Although prolactin levels continue to rise as pregnancy advances, placental sex steroids block prolactin induced secretory activity of-the glandular epithelium. Therefore, lactation is not initiated until plasma estrogens progesterone, and human placental lactogen (hPL) level fall after delivery." Suppoing hormones : * Estrogens Progestins Human placental Lactogen Stage Galactopoiesis or Maintenance of established milk secretion is mainly by sucklingdeg. Hormones responsible : Prolactindeg * Oxytocindeg Growth hormonedeg * Thyroxine/Parathyroid hormonedeg Coisoldeg * Insulindeg

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