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Pharmacology Pancreas edea4c3b

Which of the following drug is avoided in patients with diabetes and can be used for treatment of insulinoma?

A
Nicorandil
B
Minoxidil
C
Hydralazine
D
Diazoxide
High-Yield Explanation
Diazoxide - It decreases insulin --> causes hyperglycemia --> C/I in diabetics. - It is used in treatment of insulinoma. Minoxidil - Causes hair growth so it is contraindicated in young females - It is used in alopecia. Hydralazine -It is aeriodilator used in hypeension. Hydralazine- nitrate therapy are the only agents in current use that actuallyprolong life in patients with chronic hea failure. Nicorandil is a potassium channel opener. Used in angina, ischemia. S/E of nicoranidil: Palpitations, flushing.

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