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Surgery Neoplastic Disorders edbe14bc

Treatment of choice for squamous cell carcinoma of anus is?

A
Chemotherapy
B
Chemoradiation
C
Sphincter sparing surgery
D
Monoclonal antibodies
High-Yield Explanation
ANSWER: (B) ChemoradiationREF: Schwatrtz 8th ed p-1096Squamous cell carcinoma of the anal margin (distal to dentate line): treated with wide local excisionSquamous cell carcinoma of the anal canal (proximal to dentate line): chemotherapy followed by radiation (chemoradiation), abdomino perineal resection is done for residual cases.Drugs used: 5-FU, mitomycin, bleomycin, cisplatin, doxorubicinMost common anal canal cancer: squamous cell carcinoma

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