Pharmacology Osteoporosis, Sex Hormones and OCPs ed854844 The estrogen that is used in most combined hormonal contraceptives is: A Clomiphene B Ethinyl estradiol C Estrone D Norgestrel High-Yield Explanation -Most commonly used estrogen in OCPs is ethinyl estradiol. -Most commonly used progesterone in OCPs is levonorgestrel.