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Biochemistry Chemistry of Carbohydrates, Amino sugars, and Mucopolysaccharides ed747327

What can be prevented by inhibiting aldose reductase in diabetes mellitus -

A
Deafness
B
Diabetic nephropathy
C
Diabetic neuropathy
D
Diabetic cataract
High-Yield Explanation
Ans. is 'd' i.e., Diabetic cataract o When there is excessive glucose, e.g., in diabetes, it is converted to sorbitol by aldose reductose. Sorbitol is responsible for accumulates in the lens and causes diabetic cataract.

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