Condition which can present both as nephritic syndrome and nephrotic syndrome, is: March 2012

Ans: D i.e. Membranoproliferative glomerulonephritis Glomerular pathology and presentation Most frequent clinical presentation of minimal change disease is that of nephrotic syndrome Most frequent clinical presentation of acute proliferative glomerulonephritis/post-infectious glomerulonephritis is that of nephritic syndrome Most frequent clinical presentation of rapidly progressive/crescentic glomerulonephritis is that of nephritic syndrome Membranoproliferative glomerulonephritis/MPGN accounts for 10-20% of cases of nephritic syndrome in children and young adults. Some patients present only with hematuria or proteinuria in the non-nephrotic range, but many others have a combined nephritic-nephrotic picture.