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Pediatrics Acyanotic congenital hea diseases ece00993

True statement about ductus aeriosus is:

A
It undergoes anatomic closure within 24 hours of bih
B
It connects aoa with pulmonary vein
C
It is induced to close by high levels of prostaglandins
D
May cause a machinery murmur by its patency
High-Yield Explanation
IMPOANT POINTS ABOUT DUCTUS AERIOSUS: - Physiological closure: occurs almost immediately after bih by contraction of muscular wall - Anatomic closure: occurs by proliferation of intima in 10-21 days after bih - After obliteration, it forms ligamentum aeriosum. - Murmur due to PDA - Continuous machinery murmur. - Ductus aeriosus is kept open with the help of prostaglandins in ductus dependent conditions Note : Prostaglandin inhibitors are used to close the ductus aeriosus. Intravenous (IV) indomethacin or ibuprofen is used to treat patent ductus aeriosus (PDA) in premature infants.

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