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Pharmacology JIPMER 2018 ecb9eb7e

Axicabtagene ciloleucel is used in:

A
Relapsed myeloma
B
T cell lymphoma
C
Diffuse large B cell lymphoma
D
Small cell lung Ca
High-Yield Explanation
CAR T-cell therapy:- A type of treatment in which a patients T cell are changed in laboratory so they will bind to cancer cells and kill them.Blood from a vein in Patient's arm flow through a tube to an apheresis machine, which removes the T cell and sends rest of blood back to the patient. CAR T cell are grown in the lab. The CAR T cell are able to bind to antigen on cancer cell and kill them. There are 2 FDA approved CAR T cell therapies:- Axicabtagene ciloleucel- Tisagenlecleucel Axicabtagene ciloleucel is use for diffuse large B cell lymphoma

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