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Medicine Bleeding and Thrombotic Disorders ec554434

All of the following are Vitamin-K deficiency features EXCEPT:

A
Associated thrombocytopenia with prolonged bleeding
B
Deficiency is rarely seen, except in infants
C
Factor X is first to be affected
D
Warfarin causes Vitamin K deficiency
High-Yield Explanation
Ans. (a) Associated thrombocytopenia with prolonged bleedingRef: Harrison 19th ed. / 96e-8* Vitamin-K is a fat soluble compound. It promotes blood clotting by increasing hepatic biosynthesis of prothrombin and other coagulation factors.* The best sources are green leafy vegetables, liver, cheese, butter and egg yolk. Deficiency, usually seen only in neonates, in disorders of absorption or during antibiotic therapy is characterized by hemorrhage.* Warfarin acts by inhibiting Vitamin K, and does not causes deficiency of the same.

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