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Medicine General ec482b6a

A 22 year old presents to his physician with hemoptysis and hematuria with basement membrane antibodies. Most likely diagnosis is:

A
Wagner's Granulomatosis
B
Goodpasture's syndrome
C
PAN
D
Churg-Strauss syndrome
High-Yield Explanation
Answer is B (Goodpasture's Syndrome) Goodpasture's Syndrome is an autoimmune disease characterized by formation of Anti-Glomerular Basement Membrane Antibodies (Anti-GBM Antibodies) that attack both, Pulmonary Capillaries (Hemoptysis) and the Glomerulus (Hematuria) The association of Hemoptysis and Hematuria along with anti-basement membrane antibodies suggests a diagnosis of Goodpasture's Syndrome

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