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Pharmacology General ec40934f

Mechanism of action of buspirone is?

A
5 HT1A paial agonism.
B
5 HT1B antagonism.
C
5 HT1B paial agonism.
D
5 HT2C antagonism.
High-Yield Explanation
Ans. A. HT1A paial agonism5 HT1A:Presynaptic autoreceptor.Modulates serotonin release.Paial 5 HT1A agonists:Buspirone, isapirone, gepirone.Useful as anti-anxiety drug.

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