The term "tumour progression" means ?

Ans. is `d' i.e., Sequential appearance of features of increasing malignancy o Malignant neoplasm has several characterstics, that are acquired in a stepwise fashion, a phenomenon called tumor progression. o The natural history of most malignant tumors has following four phages ? Malignant change in the target stem cell --> Due to genetic or/and environmental factors stem cell is transformed into tumor cell a process is known as transformation and proliferation. Growth and proliferation of transformed cell Local invasion Metastasis